TanshinoneⅡA相关论文
Sodium Tanshinone ⅡA Sulfonate for Coronary Heart Disease:A Systematic Review of Randomized Controll
Objective:To assess whether an adjunctive therapy of Sodium Tanshinone ⅡA Sulfonate Injection (STS) is effective and sa......
Tanshinone Ⅱ A Protects against Lipopolysaccharides-Induced Endothelial Cell Injury via Rho/Rho Kina
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Tanshinone ⅡA Inhibits Dendritic Cell-mediated Adaptive Immunity: Potential Role in Anti-atheroscler
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Sodium Tanshinone ⅡA Sulfonate Ameliorates Microcirculatory Disturbance of Small Intestine by Attenu
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Due to ineffectiveness and side effects of existing analgesics, chronic pain has become one of the most complex and diff......
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Enrichment and Purification of Tanshinone ⅡA from Salvia miltiorrhiza Bunge Extracts with Macroporou
Tanshinone ⅡA,one of the most important components of Salvia miltiorrhiza Bunge,can be used for the treatment of cardio......
Background:Tendon adhesion between the sheath and tendon surface is a common clinical problem....
Glycyrrhetinic Acid-Decorated and Reduction-Sensitive Micelles for Enhancing Bioavailability and Ant
In the present study, we developed a dual-functional biodegradable micellar system named glycyrrhetinic acid-poly (ethyl......
Tanshinone Ⅱ A, the major lipophilic component of Danshen, promotes neuronal differentiation through
Danshen has been used in stroke treatment for thousands of years in China.However, the underlying mechanism still remain......
Inflammation takes responsibility for the seawater aspiration-induced lung injury.Tanshinone ⅡA (TⅡA) can protect lipo......
Tanshinone ⅡA suppresses lung injury and apoptosis and modulates AKT and ERK pathways in rats challe
1.Tanshinone ⅡA (TⅡA) is one of the main active components of the Chinese herb Danshen.In this study, we investigated ......
Tanshinone ⅡA ameliorates seawater exposure-induced lung injury by inhibiting aquaporins (AQP) 1 and
Aquaporins (AQPs), a family of transmembrane water channels, mediate physiological response to changes of fluid volume a......
The Washout with UW Solution and Tanshinone IIA to Decrease Ischemia Reperfusion Injury in Rat Ische
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Tanshinone Ⅱ A (T Ⅱ A) is widely used for the treatment of various human diseases including diabetic nephropathy (DN)1......
Efficacy and mechanism of tanshinone ⅡA liquid nanoparticles in preventing experimental postoperativ
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Tanshinone ⅡA protects Schwann cells apoptosis in mitochondrial pathway induced by intermittent high
Objective: To investigate the protective effects of Tanshinone ⅡA (Tan ⅡA) on Schwann cells (SCs) mitochondrial apopto......
Tanshinone ⅡA protects H9c2 cells from oxidative stress-induced cell death via up-regulation ofmicro
In this study the cardioprotective effect and molecular mechinsms of tanshinone ⅡA were investigated.Results showed tha......
Tanshinone ⅡA Induces Apoptosis of Cervical Cancer HeLa Cells and Advanced CaSki Cell with Proteomic
Objective Cervical cancer is one of the most common causes of mortality to females in the world.At present, paclitaxel (......
Tanshinone ⅡA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehy
Metabolic reprogramming is associated with NLRP3 inflammasome activation in activated macrophages,contributing to inflam......
The Molecular Mechanisms of Tanshinone Ⅱ A on the Apoptosis and Arrest of Human Esophageal Carcinoma
Tanshinone Ⅱ A (Tan Ⅱ A) is a monomer isolated from Salvia miltiorrhiza Bunge (Danshen) with anti-cancer effects r......
目的观察乙酰丹参酮ⅡA(ATA)对人卵巢癌细胞增殖和凋亡的诱导作用及对雌激素诱发蛋白TFF1表达的影响,探讨可能的作用机制。方法通......
目的:研究丹参酮ⅡA抑制迁移以及新生血管形成的作用机制.方法:通过MTT,2-D/3-D迁移,血管生成,PCR,CAM等方法,评价丹参酮ⅡA抑制肿......
目的探讨鞘内注射丹参酮ⅡA对骨癌痛小鼠热痛觉过敏及脊髓水平白介素-1β(IL-1β)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)表达......
目的 研究丹参酮Ⅱ A(tanshinone Ⅱ A,TSN)对大鼠.肾间质成纤维细胞转化生长因子β1(transforming growth factor β1,TGFlβ1)信......
目的 探讨水通道蛋白5(AQP5)在海水浸泡致细胞损伤中的变化,同时了解丹参酮Ⅱ A可能的作用机制.方法 体外传代培养肺腺癌细胞株A54......
目的研究丹参酮ⅡA对氧化三甲胺(TMAO)诱导的人脐静脉内皮细胞炎症损伤的抑制作用,探讨其对TMAO诱导动脉粥样硬化(AS)的治疗作用及......
目的:建立测定治疣胶囊中丹参酮ⅡA和丹酚酸B的HPLC方法。方法:采用Waters Atlantis@T3色谱柱(150 mm×4.6 mm,3μm),以乙腈-醋酸......
目的探讨丹参酮ⅡA(TSA)固体分散体制备、表征和体外溶出情况,分析其体外溶出特性。方法利用固体分散技术制备丹参酮ⅡA-PVP固体分......
目的探讨丹参酮ⅡA通过转录因子NF-E2相关因子2(Nrf2)通路对自发性高血压大鼠(SHR)的疗效及血管活性物质的影响。方法15只健康雄性......
目的探讨丹参酮ⅡA(TA)和丹酚酸(SA)B联合用药对成纤维细胞转化的影响。方法Transwell小室法检测TA和SAB对血管紧张素(Ang)Ⅱ诱导......
用乙醇回流提取法以丹参中丹参酮ⅡA含量为指标优化提取工艺。在单因素实验的基础上,对温度、料液比、浸泡时间、回流时间4个因素......
通过建立双侧颈总动脉结扎(BCCAO)大鼠模型和H_2O_2诱导的原代星形胶质细胞的氧化损伤模型,探究丹参酮ⅡA(TSA)的神经保护作用和机......
目的建立丹黄胶囊的质量标准,为其质控提供依据。方法采用薄层色谱(TLC)法对制剂中的丹参、川芎、五味子和黄芪四味药材进行定性鉴别......
目的观察丹参酮Ⅱa对HL-60的凋亡与自噬以及相关因子水平的影响,探讨丹参酮Ⅱa抗急性髓系白血病的分子机制。方法使用不同浓度的丹......
目的:采用高效液相色谱法测定组方中主药丹参所含药理活性成分丹参酮ⅡA的含量。方法:色谱柱:C1(8DaisoSp-120-5-ODS-AP4.6×250mm......
目的:研究丹参酮ⅡA对脓毒症大鼠急性肝肾损伤的治疗作用。方法:采用中线剖腹手术和盲肠结扎穿孔法将大鼠随机分为4组:假手术组(CT......
目的:探讨丹参酮ⅡA(STS)对脓毒症小鼠脑微血流和神经炎症反应的干预作用。方法:32只昆明小鼠常规开颅窗后随机分成4组:假手术组(Sham组)......
目的:体外研究丹参酮ⅡA对舌鳞状细胞癌细胞系TCA-83增殖和凋亡的影响。方法:用终浓度为0.625、1.25、2.5、5、10、20 mg/L的丹参酮......
目的丹参酮ⅡA对缺血性脑损伤大鼠的保护作用及分子机制研究。方法在造成大鼠高脂血症的基础上,进行两侧颈总动脉缺血造成脑细胞损......
目的:建立高效液相色谱法测定冠心七味滴丸中丹参酮ⅡA的含量。方法:反相高效液相色谱法,乙腈一水(70:30)为流动相,流速为1.0mi·......
目的 建立高效液相色谱法测定丹参酮ⅡA含量的方法。方法 C18柱以甲醇-水(70∶30)作为流动相,检测波长269 nm。结果 丹参酮ⅡA浓度......
目的观察丹参酮ⅡA注射液对缺血缺氧性脑损伤新生大鼠皮质神经元自噬及Akt-mTOR通路影响并探讨其机制。方法 7日龄SD新生大鼠80只,......
目的研究丹参酮ⅡA(TanⅡA)对血管紧张素Ⅱ(AngⅡ)诱导的大鼠心肌间质成纤维细胞α-平滑肌动蛋白(SMA)表达的影响。方法体外培养大鼠心肌......
目的:测定丹田胶囊中丹参酮ⅡA含量。方法采用高效液色谱法(HPLC)测定制剂中丹参酮ⅡA的含量。选择C18柱,以甲醇-水(73:27)为流动相,流速......
目的:观察宫腔黏连(IUA)模型大鼠子宫内膜中整合素αVβ3和白血病抑制因子(LIF)表达水平,探讨丹参酮ⅡA对IUA大鼠子宫内膜容受性的......
目的:观察活血化瘀类中药丹参的活性成分—丹参酮ⅡA对内皮细胞增殖的影响、及其适宜作用浓度和时间,并初步探讨其作用机制。方法:不......
目的:建立高效液相色谱法测定抗栓胶囊中丹参酮ⅡA含量。方法:采用色谱柱为Hypersil C18柱,乙腈-0.02%磷酸溶液(63∶37)为流动相,检测......
目的探讨丹参酮ⅡA(TanⅡA)对糖尿病(DM)患者外周血中内皮祖细胞的影响及可能机制。方法将62例2型DM患者随机分为对照组和实验组,实验......